Pope Leo, the first US-born pope, has come under attack from former US President Donald Trump after the pontiff made a peace appeal, criticising the US-Israeli war on Iran, in a move that has significant implications for international relations and global diplomacy, on 13 April 2026, in the Vatican.

The Pope's peace appeal is seen as a significant development in the ongoing conflict between the US, Israel, and Iran, with the pontiff emerging as an outspoken critic of the war, which has been escalating in recent months, causing widespread human suffering and destabilisation in the region. The Pope's intervention is likely to be viewed as a challenge to the US administration's foreign policy, particularly with regards to its stance on Iran, and may put pressure on the US government to reconsider its approach to the conflict. Trump's response to the Pope's appeal, describing it as "terrible for foreign policy", suggests that the former president is opposed to any attempt to question or criticise the US's role in the conflict.

The Pope's criticism of the US-Israeli war on Iran is part of a broader pattern of the Vatican's increasing involvement in international diplomacy and conflict resolution, with the Catholic Church seeking to promote peace and stability in regions affected by conflict. The Vatican's stance on the US-Israeli war on Iran is likely to be influenced by its commitment to promoting human rights, protecting civilians, and preventing further destabilisation in the region. The Pope's appeal for peace is also likely to be seen as a reflection of the Catholic Church's long-standing commitment to promoting dialogue and reconciliation in conflicts around the world. The Vatican's intervention in the conflict may be viewed as an attempt to fill a vacuum in international diplomacy, with the US and other major powers seemingly unable or unwilling to broker a peaceful resolution to the conflict.

The implications of the Pope's peace appeal and Trump's response are likely to be far-reaching, with potential consequences for international relations, global diplomacy, and the ongoing conflict between the US, Israel, and Iran. The US government may come under increased pressure to reconsider its approach to the conflict, particularly if the Pope's appeal is seen as a reflection of a broader international consensus in favour of a peaceful resolution. The Vatican's intervention may also lead to increased diplomatic efforts to resolve the conflict, with the Catholic Church potentially playing a key role in promoting dialogue and reconciliation between the parties involved. Trump's response to the Pope's appeal may also have implications for his own political legacy, with the former president's criticism of the pontiff likely to be seen as a reflection of his own polarising and divisive approach to international relations.